Astrocytic HCAR1 Activation by Tanycyte-Derived Lactate Modulates Glutamatergic Signaling and POMC Neuron Excitability
For decades, the intricate mechanisms governing appetite and satiety were predominantly attributed to the complex signaling networks of neurons, the brain’s principal electrical communicators. However, groundbreaking research published in the…
Tanycyte-Derived Lactate Activates Astrocytic HCAR1 to Modulate Glutamatergic Signaling and POMC Neuron Excitability
For decades, the intricate mechanisms governing appetite have been largely attributed to the complex interplay of neurons, the brain’s primary electrical communicators. However, a groundbreaking study published in the Proceedings…
Tanycyte-Derived Lactate Activates Astrocytic HCAR1 to Modulate Glutamatergic Signaling and POMC Neuron Excitability
For decades, the intricate machinery of the human brain, particularly its role in regulating fundamental drives like appetite, was understood through the singular lens of neurons. These highly specialized cells,…









